There is fascinating research from UMass Amherst on Naegleria tubulin ecosystem. Excerpts:

These microtubules are like the 2x4s of the cell and are used in everything from helping the cell to move, to transporting food and waste within the cell and giving the cell structural support.

One of the key moments in mitosis is when a spindle, made up of microtubules, grabs hold of the chromosomes and helps separate them into two identical sets.

Naegleria also employs three additional distinct tubulins specifically during mitosis. One pair of tubulins are used only during mitosis, while the other, the flagellate tubulin, specialize in cellular movement.

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